• Cystic fibrosis impacts growth in the womb, research shows
    on August 3, 2018 at 2:32 pm

    New research has shown that babies with cystic fibrosis are born weighing less than babies without the condition, even allowing that they are more likely to be born prematurely. […]

  • New lung cell type discovered
    on August 1, 2018 at 5:15 pm

    Two research teams report the discovery of a new, rare type of cell in the human airway. These cells appear to be the primary source of activity of the CFTR gene, mutations to which cause cystic fibrosis. […]

  • Technique may improve lung delivery of bacteria-killing phage
    on July 17, 2018 at 1:48 pm

    A new delivery system for bacteriophages -- viruses that selectively attack harmful bacteria -- could help give doctors a new way to battle lung infections that threaten older patients and people with cystic fibrosis. […]

  • Supplemental antioxidants may reduce exacerbations in cystic fibrosis
    on July 2, 2018 at 3:10 pm

    An antioxidant-enriched vitamin may decrease respiratory exacerbations in people with cystic fibrosis (CF), according to new research. […]

  • Cystic fibrosis bacterial burden begins during first years of life
    on January 19, 2018 at 7:12 pm

    Cystic fibrosis shortens life by making the lungs prone to repeated bacterial infections and inflammation. Researchers have now shown for the first time that the lungs' bacterial population changes in the first few years of life as respiratory infections and inflammation set in. This research offers a way to predict the onset of lung disease in children with CF and suggests a larger role for preventive therapies, such as hypertonic saline. […]

  • Treatment strategies for multidrug-resistant chronic infections
    on January 5, 2018 at 5:39 pm

    A new study finds that antibiotic treatment of chronic infections can be optimized by targeting vulnerabilities of antibiotic-resistant pathogens paving the way for more effective treatment strategies. […]

  • Defect in zinc supply mechanism affects pathology of intractable pulmonary diseases
    on December 28, 2017 at 3:09 pm

    Researchers revealed that abnormal delivery of zinc to lung cells contributes to obstructive pulmonary diseases. They further showed that mRNA splicing abnormalities are involved in the detailed mechanism. So far, the importance of zinc in the lung has only been understood from a nutritional aspect. This discovery is thought to be the first to clarify zinc's effects on the regulation of mRNA ligation (splicing), and its involvement in the onset of pulmonary diseases. […]

  • Protein structure could unlock new treatments for cystic fibrosis
    on December 13, 2017 at 7:36 pm

    Biochemists have used cryo-electron microscopy to determine the detailed architecture of the chloride channel TMEM16A. This protein is a promising target for the development of effective drugs to treat cystic fibrosis. […]